Assistant/Associate Research Scientist
Perspective Therapeutics
- Coralville, IA
- Permanent
- Full-time
- Drive non-clinical pipeline projects independently.
- Design and conduct experiments to support the discovery and development of theranostic radiopharmaceuticals.
- Perform routine cell culture with aseptic techniques.
- Perform molecular and cellular assays, including western blotting, PCR, enzymatic assays, ligand binding assays (i.e., Kd/Bmax, IC50, EC50)
- Prepare animal models to determine the PK/PD, therapeutic efficacy and toxicity of radiopharmaceuticals.
- Analyze experimental results and generate high-quality reports.
- Present research internally and externally and provide updates to cross-functional areas.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.Education/Experience
- Master or PhD degree in Pharmacology, Pharmaceutical Sciences, Chemistry, Biochemistry Bioengineering, Biomedical Engineering or related field.
- PhD degree or master’s degree with 5 years of working experience in research labs
- 3+ years of working experience in cancer-related fields
- 3+ years hands-on experience in developing and using murine models
- Experience with biochemical or molecular/cellular biology, such as cell-based assays, enzymatic assays, aseptic cell cultures techniques, ELISA, qPCR, etc.
- Experience with routine analytical equipment such as HPLC, TLC.
- Experience with in vivo studies using laboratory animal models.
- Experience with immunohistochemistry and flow cytometry
- Experience with radioisotopes
- Experience with wet chemistry, biology, cell culture.
- Experience with GraphPad Prism, Microsoft Office, writing and following SOPs, data analysis, statistical analysis, oral presentation
- Full range of motion and ability to use both hands mandated by machinery. High degree of manual dexterity.
- Must be able to regularly lift 10 lb. weights, occasional lifting of up to 50 lbs.
- Ability to maintain focus on a complex task for 4-6 hours at a time.
- Excellent communications, interpersonal and collaboration skills, and ability to interact professionally with a wide range of individuals and organizations, internal and external.
- Ability to work independently with minimal direction, and drive deliverables through to completion by deadlines provided.
- Highly organized with strong attention to detail and commitment to high quality work.
- Good interpersonal skills and ability to communicate information in a timely manner.
- Comfort with various computer operating systems and laboratory operational platforms.
- Ability to work within a corporate culture in which enthusiasm, respect, integrity, and teamwork are expected to the highest of standards.
- Must be willing to work in a facility producing radioactive materials and requiring all employees to participate in safety programs designed to minimize potential and/or actual exposure levels.
- Must be able to work outside of regular work hours, including off shift, weekend, and holiday work as business needs require.
- May be required to sit or stand for long periods of 8+ hours a day while performing duties.
- Occasional kneeling, crouching, twisting the upper body, bending, stooping, pushing, pulling, or reaching may be required.
- Must possess good hand-eye coordination; close attention to detail is required.
- Must be able to work indoors and outdoors with exposure to mechanical/moving parts, hazards including radioactive, corrosive, flammable and toxic material, dust, dirt, odors, and irritants.
- Must be willing to wear a variety of Personal Protective Equipment (PPE), including eye and hearing protection, as needed.
- Willingness to complete safety training within allotted timeframes, and work in a team-based environment.