Scientist, Metabolomics
Denali Therapeutics
- San Francisco, CA
- $123,000-158,000 per year
- Permanent
- Full-time
- Perform LC-MS/MS SOPs, interpret QC performance results, and troubleshoot/resolve analytical issues.
- Assist and/or lead development of new methods/SOPs for LC-MS/MS analyte detection.
- Prepare detailed laboratory notebooks and data result outputs.
- Perform routine maintenance of LC-MS/MS instruments.
- Prepare assay result summaries and present to the teams in weekly meetings and contribute to dissemination of information in scientific conferences and publications.
- Be an accountable analytical lead in developing novel assays for quantifying complex membrane lipid synthesis/turnover and for assessing cellular bioenergetics that are critical for neuronal and glial cell function.
- PhD in targeted and untargeted metabolomics and lipidomics or related scientific discipline required (or MS with 3+ years / BS with 5+ years of related industry or academic experience).
- Excellent critical thinking and scientific skills with strong fundamental backgrounds in liquid chromatography and mass spectrometry techniques.
- Experience in multi-omics data integration, interpretation, and visualization using r and/or python programming languages.
- Authored at least one first authored peer-reviewed publication in a top tier research journal.
- Ability to work effectively and collaboratively on cross-functional project teams.
- Demonstrated ability to build, interpret, and clearly communicate complex data and results through oral and written presentations.