Senior Scientist, In vivo Pharmacology, Discovery Technologies
Eli Lilly
- New York City, NY
- $76,500-138,600 per year
- Permanent
- Full-time
- Prepare drug solutions and inoculations, multiple route drug administration, animal health monitoring, anesthesia, blood samplings, necropsies, xenografts, syngeneic mouse models, humanized mouse models
- Culture tumor cells according to SOPs and contribute to the development of SOPs
- Work collaboratively with the discovery and clinical teams to support retrospective and exploratory efforts for clinical programs
- Perform cardiac, retro-orbital bleeds, and tumor injections
- Perform tumor measurements using calipers
- Harvest tumor and tissue samples from treated animals to help establish PK/PD and toxicity measurements
- Process blood and tissue samples for monitoring PD markets, hematological and tissue toxicities
- Work with the entire in vivo team to ensure all instrumentation is properly maintained and calibrated
- Proper documentation and archiving of data and analyses
- Work interactively with project teams and discovery teams to plan and execute experiments as well as be involved in data interpretation and preparation of study reports
- Work interactively with project teams as an in vivo pharmacology expert to ensure appropriate applications and priorities are considered
- Communicate results via written and oral presentations at project team meetings, be involved in the coordination and preparation of presentations
- Discuss results with technical as well as non-technical personnel
- Support archiving as well as curating data in internal databases
- Extensive cross functional communication and collaboration with internal and external parties
- Interrogate experimental conduct of third parties/vendors
- BS degree in biological sciences with 5 years of experience or MS degree in biological sciences with 2-3 years of experience required
- Extensive expertise in: in vivo pharmacology, cell line xenograft establishment, humanized mouse model systems, imaging, standard flow cytometry experiments, bioanalytical functions, small animal handling, carrying out preclinical rodent oncology modeling
- Diverse experience in cell biology and biochemical techniques to monitor PK/PD relationships
- Experience in drug discovery with regulator reporting
- Demonstrated business acumen
- Demonstrated excellence in making key strategic decisions in support of broader business goals
- Excellent written and verbal communication skills
- Flexibility to adjust priorities over time to meet organizational and scientific goals
- Ability to work independently and as an integral part of a larger collaborative team
- Demonstrated ability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines
- Excellent interpersonal, written, and verbal communication skills
- Knowledge and experience documenting and processing in vivo studies
TBD
5% The physical demands of this job are consistent with working in a lab. The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.Work Environment:
This position’s work environment is in a lab.Lilly currently anticipates that the base salary for this position could range from between $76,500 to $138,600 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Of course, the compensation described above is subject to change and could be higher or lower than the range described above. Further, Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.#WeAreLilly